| MPC Men's Basketball vs. De Anza College (Home) | 01/26/2022 5:00 PM | |
| MPC Women's Basketball vs. DeAnza College (Home) | 01/26/2022 7:00 PM | |
| MPC Men's Basketball vs. Gavilan College (Home) | 01/28/2022 5:00 PM | |
| MPC Women's Basketball vs. Hartnell College (Home) | 02/02/2022 5:00 PM | |
| MPC Men's Basketball vs. Hartnell College (Away) | 02/02/2022 7:00 PM | |
| MPC Women's Basketball vs. San José City College (Home) | 02/04/2022 5:00 PM | |
| MPC Men's Basketball vs. San Jose City College (Home) | 02/04/2022 7:00 PM | |
| MPC Men's Basketball vs. West Valley College (Away) | 02/11/2022 7:00 PM | |
| MPC Women's Basketball vs. Mission College (Away) | 02/11/2022 7:00 PM | |
| MPC Men's Basketball vs. Cabrillo College (Home) | 02/16/2022 5:00 PM | |
| MPC Women's Basketball vs. Cabrillo College (Soph Night) (Home) | 02/16/2022 7:00 PM | |
| MPC Women's Basketball vs. DeAnza College (Away) | 02/18/2022 5:00 PM | |
| MPC Men's Basketball vs. De Anza College (Away) | 02/18/2022 7:00 PM | |
| MPC Men's Basketball 1st Round Regional Playoffs | 02/23/2022 | |
| MPC Men's Regional Quarterfinals | - | |
| MPC Men's Basketball Regional Quarterfinals | - | |
| MPC Men's Basketball Sweet Sixteen | 03/04/2022 | |
| MPC Men's Basketball Elite Eight (NorCal) | - | |
| MPC Men's Basketball Sophomore Showcase | 03/11/2022 | |
| Track & Field De Anza Invitational | 03/19/2022 | |
| Women's Tennis vs. Canada College (Home) | 03/22/2022 11:00 AM - 3:00 PM | |
| Baseball vs. Cabrillo College (Home) | 03/22/2022 2:30 PM - 5:30 PM | |
| Baseball vs. Cabrillo College (Away) | 03/24/2022 2:30 PM - 5:30 PM | |
| W's Softball vs. Chabot College (Away) | 03/24/2022 3:00 PM - 5:00 PM | |
| Beach Volleyball vs. Gavilan College (Away) | 03/25/2022 12:00 PM - 1:30 PM | |
| Beach Volleyball vs. De Anza College (Away) | 03/25/2022 1:30 PM - 3:00 PM | |
| Women's Tennis vs. Mission College (Home) | 03/25/2022 2:00 PM - 6:00 PM | |
| Track & Field Cal Poly Invitational | 03/26/2022 | |
| W's Softball vs. Alan Hancock College (Home) | 03/26/2022 1:00 PM - 3:00 PM | |
| Baseball vs. Mission College (Home) | 03/26/2022 1:00 PM - 4:00 PM | |
| W's Softball vs. Alan Hancock College (Home) | 03/26/2022 3:00 PM - 5:00 PM | |
| Women's Tennis vs. Chabot College (Away) | 03/29/2022 2:00 PM - 6:00 PM | |
| Baseball vs. Chabot College (Away) | 03/29/2022 2:30 PM - 5:30 PM | |
| W's Softball vs. College of San Mateo (Home) | 03/29/2022 3:00 PM - 5:00 PM | |
| Track & Field Chabot College Invitational | 03/31/2022 | |
| Baseball vs. West Valley College (Home) | 03/31/2022 2:30 PM - 5:30 PM | |
| Track & Field West Coast Relays | 04/01/2022 | |
| Beach Volleyball vs. College of San Mateo (Away) | 04/01/2022 12:00 PM - 1:30 PM | |
| Beach Volleyball vs. Fresno City College (Away) | 04/01/2022 3:00 PM - 4:30 PM | |
| W's Softball vs. Merced College (Home) | 04/02/2022 12:00 PM - 2:00 PM | |
| Baseball vs. Canada College (Away) | 04/02/2022 1:00 PM - 4:00 PM | |
| W's Softball vs. Merced College (Home) | 04/02/2022 2:00 PM - 4:00 PM | |
| Baseball vs. Mission College (Away) | 04/05/2022 2:30 PM - 5:30 PM | |
| W's Softball vs. Cabrillo College (Away) | 04/05/2022 3:00 PM - 5:00 PM | |
| Baseball vs. Hartnell College (Away) | 04/07/2022 2:30 PM - 5:30 PM | |
| W's Softball vs. San Jose City College (Away) | 04/07/2022 3:00 PM - 5:00 PM | |
| Beach Volleyball vs. West Valley College (Away) | 04/08/2022 1:00 PM - 2:30 PM | |
| Beach Volleyball vs. Cabrillo College (Away) | 04/08/2022 2:30 PM - 4:00 PM | |
| Track & Field Sacramento State Invitational | 04/09/2022 | |
| W's Softball vs. Hartnell College (Away) | 04/09/2022 11:00 AM - 1:00 PM | |
| W's Softball vs. Hartnell College (Away) | 04/09/2022 1:00 PM - 3:00 PM | |
| Baseball vs. Hartnell College (Home) | 04/09/2022 1:00 PM - 4:00 PM | |
| Baseball vs. De Anza College (Away) | 04/12/2022 2:30 PM - 5:30 PM | |
| W's Softball vs. West Valley College (Away) | 04/12/2022 3:00 PM - 5:00 PM | |
| W's Softball vs. Hartnell College (Home) | 04/14/2022 3:00 PM - 5:00 PM | |
| Beach Volleyball vs. Gavilan College (Home) | 04/15/2022 12:00 PM - 1:30 PM | |
| Beach Volleyball vs. De Anza College (Home) | 04/15/2022 3:00 PM - 4:30 PM | |
| Baseball vs. Ohlone College (Home) | 04/16/2022 1:00 PM - 4:00 PM | |
| Baseball vs. Ohlone College (Away) | 04/19/2022 2:30 PM - 5:30 PM | |
| Baseball vs. Cabrillo College (Home) | 04/21/2022 2:30 PM - 5:30 PM | |
| W's Softball vs. Cabrillo College (Home) | 04/21/2022 3:00 PM - 5:00 PM | |
| Track & Field Mustang Invitational | 04/22/2022 | |
| Beach Volleyball vs. College of San Mateo (Away) | 04/22/2022 1:30 PM - 3:00 PM | |
| Beach Volleyball vs. Fresno City College (Away) | 04/22/2022 4:30 PM - 6:00 PM | |
| Track & Field Hartnell Last Chance | 04/23/2022 | |
| Baseball vs. Cabrillo College (Away) | 04/23/2022 1:00 PM - 4:00 PM | |
| Track & Field Coast Conference Championships (Trials) | 04/26/2022 | |
| Baseball vs. Mission College (Away) | 04/26/2022 2:30 PM - 5:30 PM | |
| Baseball vs. Mission College (Home) | 04/28/2022 2:30 PM - 5:30 PM | |
| Track & Field Coast Conference Championships (Finals) | 04/29/2022 | |
| Track & Field Nor Cal Championships (Trials) | 05/06/2022 | |
| Track & Field Nor Cal Championships (Finals) | 05/13/2022 | |
| MPC Football at Reedley College (Away) | 08/20/2022 12:00 PM | |
| MPC Men's Soccer vs Clovis | 08/26/2022 4:00 PM | |
| MPC Men's Soccer at West Hills Lemore | 08/30/2022 4:00 PM | |
